Her 4
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v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
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Identifiers | |
Symbol | ERBB4 |
HUGO | 3432 |
Entrez | 2066 |
OMIM | 600543 |
RefSeq | NM_001042599 |
UniProt | Q15303 |
Other data | |
Locus | Chr. 2 q34 |
Her-4 is a member of the EGFR family of receptor tyrosine kinases. Like EGFR, Her-4 is able to bind to several activating ligands and dimerize with every other member of the EGFR family.
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Angiopoietin Receptors: Tie-1 & Tie-2 - Eph - Epidermal growth factor (HER2/neu, Her 3, Her 4) - Fibroblast growth factor (FGFR2) - Flk-1 Flt-1 Insulin - IGF-1 - MuSK - Platelet-derived growth factor - TRK (TrkA, TrkB, TrkC), VEGF Receptors: Flt-1 & KDR/Flk-1,