Talk:Hepatocellular carcinoma

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In hepatocellular carcinoma , there is high level of serum copper and copper to zinc ratio as the serum zinc level is low.Is this interesting to measure the serum copper and zinc level?

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Contents

[edit] Liver cancer

Since liver cancer is not synonym for hepatocellular carcinoma, I turned liver cancer, which was previously a redirect to here, to a disambiguation page. --Steven Fruitsmaak 12:50, 22 May 2006 (UTC)

Also, I think the translations should be different, not translating "liver cancer" but "hepatocellular carcinoma". --Steven Fruitsmaak 17:25, 25 May 2006 (UTC)

[edit] HCC

Please redirect from HCC.

[edit] Hepatoma

>(an alternative name may be hepatoma) This was originally mentioned after the name. However, hepatomas are generally benign and harmless, which cannot be said about HCC Jfdwolff 00:05, 27 Feb 2004 (UTC)

Hepatoma is an old name for primary hepatocellular carcinoma. [Yes, it's a misnomer.] Axl 18:18, 3 Jan 2005 (UTC)

So hepatoma should be a disambiguation. JFW | T@lk 21:00, 3 Jan 2005 (UTC)
Eh? With respect, I think that you made a mistake. Hepatoma = hepatocellular carcinoma. Axl 12:14, 5 Jan 2005 (UTC)

So what do you call benign liver neoplasms, if not hepatoma? JFW | T@lk 16:04, 5 Jan 2005 (UTC)

I call them benign liver tumours/cysts/adenomas. Axl 09:54, 6 Jan 2005 (UTC)

Good, it must be my training abroad that's leading to the confusion :-) JFW | T@lk 21:11, 6 Jan 2005 (UTC)

Hehe! :-) It is exactly this sort of confusion that caused the word (hepatoma) to fall into disuse. It doesn't comply with the general rule that solid epithelium-derived cancers should be designated 'carcinoma'. Axl 21:28, 6 Jan 2005 (UTC)

[edit] Some Questions

Is Aspergillus responsible for a "unique" type of HCC ? I wasn't aware of there being a big difference between the two forms, and also leaves us with the problem of what to do with those who have both Hep B and Aflatoxin (e.g. in West Africa) MattW 12:35, 26 July, 2005

Is this interesting to measure serum copper and Cu/Zn ratio in HCC?

[edit] Reverts

Dear Jfdwolff -- I think we need to revise the treatment section, or perhaps add a research heading, where we could link to clinical trials and current research -- the reason is that this may help patients -- What do you think? Anita Brenner

I agree, but please adhere to the manual of style. JFW | T@lk 06:29, 16 May 2005 (UTC)

JFW: Your reverts eliminated my references to screening tests, Dr. So's genetics research, even reference sites for patients and this week's ASCO abstracts.

I see by the history that you have reverted every time some one wanders in and posts a new link. All the links I have seen in the history, the ones that you erase, appear to be valid resources.

You describe yourself as a physician, so I don't understand why you want to deprive patients of full access to the vast array of online resources, particularly when they may be of more benefit than the outdated summary you keep reverting to.

What's the problem?

Anita Brenner

Anita, please don't be insulted by something so minor, and try not to attack me without hearing me out. As you have recently joined you have not yet have seen how some articles are continuously "updated" by people wanting every detail mentioned of the most obscure research, theories and sometimes worse.
Wikipedia does not need external links. What Wikipedia needs is a well-written clear outline, not just of frontline research but of basic principles such as staging, histology and prognosis. Readers are much more helped by the conclusions of a recent review paper than by a deluge of links.
I hope this explains my "record" of removing added links. Please cooperate - I think this article needs a lot of work and it has a lot of worldwide implications (its highest incidence being in Southeast Asia). JFW | T@lk 12:39, 16 May 2005 (UTC)

What Wikipedia needs is a well-written clear outline, not just of frontline research but of basic principles such as staging, histology and prognosis. That's very nice: are you actually going to do this or just remove anyone else's contributions? And since you've set yourself up as a veteran here, perhaps you ought to reacquaint yourself with Don't bite the newcomers and lose the supercilious attitude. --Calton | Talk 14:47, 16 May 2005 (UTC)

Oh, you've posted it here and on my talkpage? My response was intended to be constructive, so please do not make it sound differently. I'm honestly interested in Anita's expertise, and I don't think she needs you to come to her defense. JFW | T@lk 15:14, 16 May 2005 (UTC)
  • Dear Calton, thank you for sticking up for me. I appreciate it.
  • This is long, but since it is my last post on Wikipedia, please bear with me.
  • Calton is correct, . I am not the first newcomer to attempt to contribute to this page, to try to bring it current, but, as the history of this and other page suggests, Jfdwolff, is brutal to newcomers.


  • Wikipedia had the opportunity to clear up a confusing area for people who are diagnosed with HCC. When I came upon this page, Jfdwolff had spent more time on political statements (he seems not to like the USA very much) than he did on current treatments and research. So in good faith, I thought I would make a contribution. But Jfdwolff kept reverting everything.
  • Because Jfdwolff chases away newcomers and automatically reverts most revisions, this page, in particular, is out of date.
  • Thanks to Calton, Jfdwolff has finally, kicking and screaming, grudgingly kept a few of the links that I contributed.
  • However, Jfdwolff has marginalized some of the links by relegating them to a special section. For example, Jfdwolff mischaracterizes the Wilson site as mere "patients' links." Unlike Jfdwolff, the Wilsons have raised money to publish a handbook for HCC patients. That booklet was written and approved by phyisicians on their board. Their booklet is more current and better written than anything jfdwolff has written here.


  • Why did I write that page and why did I take the time to share all these resources here? Because the doubling time of HCC is 1-3 months and bioinformatics is essential. Patients and their physician need quick access to the latest research abstracts from ASCO, journal abstracts from Pubmed, clinical trial results. They also need to know what drugs are in the pipeline and how approved drugs can be used off-label.
  • But, life is too short to waste time where one is not wanted. Jfdwolff, I prefer to spend my time raising money for cancer research, and supporting the fine physicians and patients at the forefront of this disease. Some day Cancer will be a disease of the past.
  • And yes, JfdWolff, I do object to your citation to the Brazilian Journal of Medical Biology as a background review. The NIH, MD Anderson, NCI and ASCO sites are far better for background information. But they don't fit in to your political world view.

Ciao, JfdWolff, You win.


17 May 2005 Anita Brenner

Does anyone object against this article (Franca AV, Elias Junior J, Lima BL, Martinelli AL, Carrilho FJ. Diagnosis, staging and treatment of hepatocellular carcinoma. Braz J Med Biol Res 2004;37:1689-705. PMID 15517086) as a background review? JFW | T@lk 15:50, 16 May 2005 (UTC)

[edit] Restoration of content

I found a lot of content removed in this edit, by an anon with one edit. I've restored the lost content, but there have been some minor changes made since then that are now lost. I think this is the proper action, but if anyone disagrees, let me know. --Arcadian 01:51, 29 January 2006 (UTC)

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