Guanosine triphosphate

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Guanosine triphosphate
Other names guanosine-5'-triphosphate, 9-β-D-ribofuranosylguanine-5'-triphosphate, 9-β-D-ribofuranosyl-2-amino-6-oxo-purine-5'-triphosphate
Identifiers
CAS number [86-01-1]
MeSH Guanosine+triphosphate
Properties
Molecular formula C10H16N5O14P3
Molar mass 523.18
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Guanosine triphosphate (GTP) is a purine nucleotide. Its main role is as substrate for the synthesis of RNA during transcription.

It also has the role of a source of energy or an activator of substares in metabolic reactions, like that of ATP, but more specific. It is used as a source of energy for protein synthesis.

GTP is essential to signal transduction, particulary with G-proteins, where it is converted to GDP (guanosine diphosphate) through the action of GTPases.

[edit] Energy transfer

GTP is involved in energy transfer within the cell. For instance, one GTP molecule is generated for every turn of the citric acid cycle. This is tantamount to the generation of one molecule of ATP since GTP is readily converted to ATP.


[edit] External links


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Major Families of Biochemicals
Peptides | Amino acids | Nucleic acids | Carbohydrates | Lipids | Terpenes | Carotenoids | Tetrapyrroles | Enzyme cofactors | Steroids | Flavonoids | Alkaloids | Polyketides | Glycosides
Analogues of nucleic acids: Types of Nucleic Acids Analogues of nucleic acids:
Nucleobases: Adenine | Thymine | Uracil | Guanine | Cytosine | Purine | Pyrimidine
Nucleosides: Adenosine | Uridine | Guanosine | Cytidine | Deoxyadenosine | Thymidine | Deoxyguanosine | Deoxycytidine
Nucleotides: AMP | UMP | GMP | CMP | ADP | UDP | GDP | CDP | ATP | UTP | GTP | CTP | cAMP | cADPR | cGMP
Deoxynucleotides: dAMP | TMP | dGMP | dCMP | dADP | TDP | dGDP | dCDP | dATP | TTP | dGTP | dCTP
Ribonucleic acids: RNA | mRNA | piRNA | tRNA | rRNA | ncRNA | sgRNA | shRNA | siRNA | snRNA | miRNA | snoRNA | LNA
Deoxyribonucleic acids: DNA | mtDNA | cDNA | plasmid | Cosmid | BAC | YAC | HAC
Analogues of nucleic acids: GNA | PNA | TNA | morpholino