Glucose-1-phosphate

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Glucose-1-phosphate
Identifiers
CAS number [59-56-3]
PubChem 65533
MeSH glucose-1-phosphate
Properties
Molecular formula C6H13O9P
Molar mass 260.136
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references
Ball and stick model of Glucose 1-phosphate
Ball and stick model of Glucose 1-phosphate

Glucose 1-phosphate (also called cori ester) is a glucose molecule with a phosphate group on the 1'-carbon.

It is the direct product of the reaction in which glycogen phosphorylase cleaves off a molecule of glucose from a greater glycogen structure. To be utilized in cellular catabolism it must first be converted to glucose 6-phosphate by the enzyme phosphoglucomutase. One reason that cells form glucose-1-phosphate instead of glucose during glycogen breakdown is that the very polar phosphorylated glucose cannot leave the cell mebrane and so is marked for intracellular catabolism.

Free glucose 1-phosphate can also react with UTP to form UDP-glucose. It can then return to the greater glycogen structure via glycogen synthase.

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