Gingival hyperplasia
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Gingival hyperplasia is a condition characterized by hyperplasia, or enlargement, of the gingiva, or gums. It is commonly seen in Boxer dogs and other brachycephalic breeds,[1] and in the Springer Spaniel.[2] It usually starts around middle age and progresses. Some areas of the gingiva can become quite large but have only a small attachment to the rest of the gingiva. It may completely cover the teeth. Infection and inflammation of the gingiva is common with this condition. Under anesthesia the enlarged areas of gingiva can be cut back with a scalpel blade, but it usually recurs. Gingival hyperplasia is also a potential sequela of gingivitis. In dogs it may be seen as a side effect to the use of cyclosporin.[3]
In humans, gingival hyperplasia can be caused by a dose-dependent reaction to certain drugs, e.g. the anti-convulsant phenytoin, cyclosporin, and calcium channel blockers.[4]
[edit] References
- ^ Gingival Fibroma and Epulides. The Merck Veterinary Manual (2006). Retrieved on March 8, 2007.
- ^ Gorrel, Cecilia (2003). Periodontal Disease. Proceedings of the 28th World Congress of the World Small Animal Veterinary Association. Retrieved on March 25, 2007.
- ^ Guaguère E, Steffan J, Olivry T (2004). "Cyclosporin A: a new drug in the field of canine dermatology". Vet Dermatol 15 (2): 61-74. PMID 15030555.
- ^ Nishikawa S, Nagata T, Morisaki I, Oka T, Ishida H (1996). "Pathogenesis of drug-induced gingival overgrowth. A review of studies in the rat model". J Periodontol 67 (5): 463-71. PMID 8724703.