Talk:Genetic marker

From Wikipedia, the free encyclopedia

WikiProject Medicine This article is within the scope of WikiProject Medicine. Please visit the project page for details or ask questions at the doctor's mess.
Stub rated as stub-Class on the assessment scale
??? This article has not yet received an importance rating on the assessment scale.
Molecular and Cellular Biology WikiProject This article is within the scope of the Molecular and Cellular Biology WikiProject. To participate, visit the WikiProject for more information. The current monthly improvement drive is Signal transduction.

Article Grading: The article has not been rated for quality and/or importance yet. Please rate the article and then leave comments here to explain the ratings and/or to identify the strengths and weaknesses of the article..

[edit] Note

that "genetic marker", in a medical dictionary, will have a definition like:
genetic marker n. A gene phenotypically associated with a particular, easily identified trait and
used to identify an individual or cell carrying that gene

but in geneology studies, it mostly refers to "junk DNA" areas.

A marker isn't necessarily associated with a phenotype. It's just a "unique" sequence. That is, di, tri, and tetranucleotide repeats aren't unique in the usual sense. But the number of repeats can make it a good identifier. Also, the uniqueness needn't be global. Usually we're only concerned with a small sub-population. The markers must be somewhat unique within the sub-population in order to be of any use. If it's a marker than everyone has, it's not a marker, just part of the normal DNA sequence. neffk 03:52, 24 January 2007 (UTC)



Yes, this page needs work: the above comment was more directly helpful to me than the article. Is anyone working on this? wasserperson 21:33, 16 December 2005 (UTC)

[edit] Isozymes not genetic markers?

The article Isozymes says that isozymes are genetic markers, but describes them as being enzymes with the same function but coming from different loci, while this article states that genetic markers have to be easily identifiable, associate with a specific locus . I'm confused.