Gamma glutamyl transpeptidase

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gamma-glutamyltransferase 1
Identifiers
Symbol	GGT1 GGT
HUGO	4250
Entrez	2678
OMIM	231950
RefSeq	NM_001032364
UniProt	P19440
Other data
EC number	2.3.2.2
Locus	Chr. 22 q11.1-11.2

gamma-glutamyltransferase 2
Identifiers
Symbol	GGT2 GGT
HUGO	4251
Entrez	2679
OMIM	137181
RefSeq	NM_002058
UniProt	P36268
Other data
EC number	2.3.2.2
Locus	Chr. 22 q11.1-11.2

gamma-glutamyltransferase 3
Identifiers
Symbol	GGT3
HUGO	4252
Entrez	2680
Other data
EC number	2.3.2.2
Locus	Chr. 22 [1]

Gamma glutamyl transferase (GGT or GGTP, or Gamma-GT) (EC 2.3.2.2) is a liver enzyme.

1 Function
2 Location
3 Clinical significance
4 References

[edit] Function

It is involved in the transfer of amino acids across the cellular membrane and in glutathione metabolism.

[edit] Location

GGT is found in high concentrations in the liver, bile ducts and kidney.

The enzyme is also present in other tissues, such as the epididymis.

[edit] Clinical significance

Its level in the blood may be tested for, as an elevated level may indicate an abnormality in the liver, though this can be caused by a number of conditions including: