Gamma-glutamylcysteine synthetase

From Wikipedia, the free encyclopedia

You have new messages (last change).

Gamma-glutamylcysteine synthetase (EC 6.3.2.2) is the first enzyme in the glutathione biosynthesis pathway. It catalyses the ATP-dependent condensation of cysteine and glutamate to form the dipeptide gamma-glutamylcysteine. The peptide bond in this peptide product is between the carboxylate group of the glutamate and the amino group of the cysteine.[1]

[edit] References

  1. ^ Njålsson R, Norgren S (2005). "Physiological and pathological aspects of GSH metabolism.". Acta Paediatr 94 (2): 132-7. PMID 15981742. 


 This enzyme-related article is a stub. You can help Wikipedia by expanding it.
Retrieved from "http://en.wikipedia.org../../../g/a/m/Gamma-glutamylcysteine_synthetase.html"