Image:G protein signal transduction (epinephrin pathway).png

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Description

Epinephrine binds its receptor, that associates with an heterotrimeric G protein. The G protein associates with adenylate cyclase that converts ATP to cAMP. This initiates a chain of chemical reactions to ultimately signal a cellular response. Four PDB structures were used in this picture: 1f88 (links to Rhodopsin!?), 1got, 1cul, and 1tbg, from left to right. (more details...)

Source

Molecule of the Month by www.pdb.org (see the Molecule of the Month section for more details)

Date

Year 2004 (see the complete list for more details)

Author

Illustration by David S. Goodsell of The Scripps Research Institute (see this site)

Permission

Original work of the US Federal Government - public domain

Public domain This work is in the public domain in the United States because it is a work of the United States Federal Government under the terms of Title 17, Chapter 1, Section 105 of the US Code. See Copyright.

Note: This only applies to works of the Federal Government and not to the work of any individual U.S. state, territory, commonwealth, county, municipality, or any other subdivision.


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