Friedrich Daniel von Recklinghausen

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Friedrich Daniel von Recklinghausen ( December 2, 1833, Gütersloh, Westfalen - August 26, 1910, Strasbourg) was a German pathologist who practiced medicine in Würzburg and Strasbourg.

In 1882 he released a monograph which reviewed previous literature and characterized the tumors of Neurofibromatosis type 1 or NF-1 as neurofibromas, consisting of an intense commingling of nerve cells and fibrous tissue. It was once thought that Joseph Merrick, the "Elephant Man" was afflicted with neurofibromatosis type I, however it is now believed that Merrick suffered from Proteus syndrome, or a possible combination of the two diseases.

Von Recklinghausen was the first to make the link between haemochromatosis and iron accumulation in body tissue, a disease first described in 1865 by Armand Trousseau. Von Recklinghausen published his findings in Hämochromatose, Tageblatt der Naturforschenden Versammlung. He also established a method of staining the lines of cell junctions with silver, a procedure that led to Julius Friedrich Cohnheim’s research on leukocyte migration and inflammation.

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