Fixed effect model

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Fixed effect(s) model is a term often used in hierarchical linear modeling. It is an opposite of a random effect model. Fixed effect model assumes that the data come from normal populations which differ in their means. It answers the question whether the studies included in the meta-analysis show that the treatment or exposure produced the effect on average.

In a fixed effect model the unit of analysis are the ones of interest, and thus constitute the entire population of units. Only within-study variation is taken to influence the uncertainty of results (as reflected in the confidence interval) of a meta-analysis using a fixed effect model. Variation between the estimates of effect from each study (heterogeneity) does not effect the confidence interval in a fixed effect model.

Methods often used with fixed effect model:

  • Mantel Haenszel method
  • Peto's method
  • General variance-based method

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