Ferrochelatase

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ferrochelatase
Identifiers
Symbol FECH
HUGO 3647
Entrez 2235
OMIM 177000
RefSeq NM_000140
UniProt P22830
Other data
EC number 4.99.1.1
Locus Chr. 18 q21.2-21.3

Ferrochelatase is an enzyme involved in the eighth step of porphyrin metabolism, converting protoporphyrin IX into heme. It catalyses reaction: protoporphyrin + Fe(2+) = protoheme + 2 H(+). A ferrochelatase enzyme consists of 497 amino acid residues with a m.w. of 55.4 kDa.

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