Famciclovir

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Famciclovir
Systematic (IUPAC) name
[2-(acetyloxymethyl)-4-(2-aminopurin-9-yl)-butyl] acetate
Identifiers
CAS number 104227-87-4
ATC code J05AB09 S01AD07
PubChem 3324
DrugBank APRD00600
Chemical data
Formula C14H19N5O4 
Mol. mass 321.332 g/mol
Physical data
Melt. point 103 °C (217 °F)
Pharmacokinetic data
Bioavailability 75–77%
Protein binding 20-25%
Metabolism Hepatic, circulation, intestinal wall (to penciclovir)
Half life 2–2.3 hours
Excretion Renal, faecal
Therapeutic considerations
Pregnancy cat.

B1 (Au), B (U.S.)

Legal status

S4 (Au), POM (UK), ℞-only (U.S.)

Routes Oral

Famciclovir (INN) (IPA: [pɛnˈsaɪklovir]) is a guanine analogue antiviral drug used for the treatment of various herpesvirus infections, most commonly for herpes zoster (shingles). It is a prodrug form of penciclovir with improved oral bioavailability. Famciclovir is marketed under the trade name Famvir (Novartis).

In Korean it is sold under the brand name 팜시바 with the generic name of 팜시클바.

Side effects: mild to extreme stomach upset, headaches, mild fever.

[edit] See also

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