Evans blue

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For the band, see Evans Blue
Evans blue
Identifiers
CAS number [314-13-6]
PubChem 6321418
MeSH Evans+blue
Properties
Molecular formula C34H24N6Na4O14S4
Molar mass 960.809
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox disclaimer and references

Evans blue is a dye which has a very high affinity for serum albumin.

Because of this, it can be useful in physiology in estimating the proportion of body water contained in blood plasma.[1]

Evans blue is also used to assess the permeability of the blood-brain barrier to macromolecules. Because serum albumin cannot cross the barrier, normally the neural tissue remains unstained.[2]

[edit] See also

[edit] References

  1. ^ Physiology at MCG 7/7ch02/7ch02p17
  2. ^ Hawkins BT, Egleton RD (2006). "Fluorescence imaging of blood-brain barrier disruption". Journal of Neuroscience Methods 151 (2): 262-7. 

[edit] External links

  • el-Sayed H, Goodall S, Hainsworth R (1995). "Re-evaluation of Evans blue dye dilution method of plasma volume measurement". Clin Lab Haematol 17 (2): 189-94. PMID 8536425. 
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