EHNA
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EHNA
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Systematic (IUPAC) name | |
3-(6-aminopurin-9-yl)nonan-2-ol hydrochloride | |
Identifiers | |
CAS number | |
ATC code | ? |
PubChem | |
Chemical data | |
Formula | C14H24ClN5O |
Mol. mass | 313.826 g/mol |
Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | ? |
Half life | ? |
Excretion | ? |
Therapeutic considerations | |
Pregnancy cat. |
? |
Legal status | |
Routes | ? |
EHNA (erythro-9-(2-hydroxy-3-nonyl)adenine) is a phosphodiesterase inhibitor that selectively inhibits phosphodiesterase type-2 (PDE2).[1]
[edit] References
- ^ Podzuweit T, Nennstiel P and Muller A (1995)Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine. Cell Signal. 7:733-8. PMID 8519602
Phosphodiesterase inhibitors (C01CE, G04BE) | Selective|
---|---|
PDE1 | Vinpocetine |
PDE2 | EHNA |
PDE3 | Amrinone, Bucladesine, Enoximone, Milrinone |
PDE4 | Mesembrine, Rolipram |
PDE5 | Sildenafil, Tadalafil, Vardenafil |