Echinocandin

From Wikipedia, the free encyclopedia

Echinocandins are antifungal drugs that inhibit the synthesis of glucan in the cell wall, probably via the enzyme 1,3-β glucan synthase. They are fungicidal against yeast and fungistatic against mold.

• Anidulafungin
• Caspofungin
• Micafungin

[edit] References

• Wagner C, Graninger W, Presterl E, Joukhadar C (2006). "The echinocandins: comparison of their pharmacokinetics, pharmacodynamics and clinical applications". Pharmacology 78 (4): 161-77. PMID 17047411. 
• Morris M, Villmann M (2006). "Echinocandins in the management of invasive fungal infections, part 1". Am J Health Syst Pharm 63 (18): 1693-703. PMID 16960253. 
• Morris M, Villmann M (2006). "Echinocandins in the management of invasive fungal infections, Part 2". Am J Health Syst Pharm 63 (19): 1813-20. PMID 16990627.