DTPA

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DTPA
Structure of DTPA
General
Systematic name (Carboxymethyl)iminobis(ethylenenitrilo)]-

tetra-acetic acid

Other names DTPA, Diethylenetriaminepentaacetic acid,

Diethylenetriamine-N,N,N',N',N-pentaacetic acid,

N,N-Bis(2-(bis-(carboxymethyl)amino)ethyl)-glycine,

Pentetic acid

Molecular formula C14H23N3O10
SMILES  ?
Molar mass 393.3498 g/mol
Appearance White crystalline solid
CAS number [67-43-6]
Properties
Density and phase  ? g/cm³, ?
Solubility in water <0.5g/100ml
Melting point 220°C (493.15 K, 428°F)
Boiling point decomposes at a higher temp.
Acidity (pKa)  ?
Basicity (pKb)  ?
Chiral rotation [α]D  ?°
Viscosity  ? cP at ?°C
Structure
Molecular shape  ?
Coordination
geometry
 ?
Crystal structure  ?
Dipole moment  ? D
Hazards
MSDS External MSDS
Main hazards  ?
NFPA 704
Flash point Does not burn
R/S statement R: ?
S: ?
RTECS number MB8205000
Supplementary data page
Structure and
properties
n, εr, etc.
Thermodynamic
data
Phase behaviour
Solid, liquid, gas
Spectral data UV, IR, NMR, MS
Related compounds
Other anions  ?
Other cations  ?
Related ?  ?
Related compounds EDTA, NTA
Except where noted otherwise, data are given for
materials in their standard state (at 25°C, 100 kPa)
Infobox disclaimer and references

Diethylene triamine pentaacetic acid (DTPA) is an elongated version of EDTA. It has been used to decontaminate humans who are contaminated with plutonium, americium and other actinides as the compound can chelate these heavy metal ions, render them unabsorbed through the digestive tract and also speeds up the release of these metals in urine. It is normally used as the calcium or zinc salt. It should not be taken by people with kidney disease or bone marrow depression, nor by children younger than 18 years old. If the lungs are contaminated by the inhalation of these radioactive materials, a DTPA spray or mist is used. Otherwise it can also be injected intravenously.

Uses: It is used as a soil extractant for available soil micronutrients like Zn,Fe,Cu and Mn at the pH of 7.3 with Calcium chloride and TEA. Furthermore, it is used as to chelate gadolinium to form a MRI contrast agent, such as Magnevist

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