Dihydrobenzophenanthridine oxidase

From Wikipedia, the free encyclopedia

Dihydrobenzophenanthridine oxidase (DHBP oxidase) is an enzyme. In the IUBMB Enzyme Nomenclature, Dihydrobenzophenanthridine oxidase is EC 1.5.3.12. Dihydrobenzophenanthridine oxidase/EC 1.5.3.12 produces oxidized forms of benzophenanthridine alkaloids:

• In Sanguinaria Canadensis EC 1.5.3.12 produces sanguinarine from dihydrosanguinarine, and chelirubine from dihydrochelirubine.
• In California poppy, EC 1.5.3.12 produces macarpine from dihydromacarpine.

[edit] External links

• EC 1.5.3.12 International Union of Biochemistry and Molecular Biology, Recommendations on Biochemical & Organic Nomenclature, Symbols & Terminology etc., web interface.
• Chelirubine, Macarpine, and Sanguinarine Biosynthesis ibid.
• Elicitation of dihydrobenzophenanthridine oxidase in Sanguinaria canadensis cell cultures Atanas Ignatov, W. Gregg Clark, Steven D. Cline, Mikulas Psenak, Robert J. Krueger, and Carmine J. Coscia, Phytochemistry, Vol 43, Issue 6, December 1996, pp. 1141-1144 (doi:10.1016/S0031-9422(96)00540-7)
• Antisense RNA-Mediated Suppression of Benzophenanthridine Alkaloid Biosynthesis in Transgenic Culture of California Poppy Sang-Un Park, Min Yu, Peter J. Facchini, Plant Physiol, February 2002, Vol. 128, pp. 696-706
• Growth Characteristics of Sanguinaria canadensis L. cell suspensions and immobilized cultures for production of benzophenanthridine alkaloids. Rho D, Chauret N, Laberge N, Archambault J., Appl. Microbiol. Biotechnol. Feb 1992;36(5):pp. 611-7.
• KEGG (Kyoto Encyclopedia of Genes and Genomes) Alkaloid biosynthesis I - Reference pathway