Dialysis adequacy
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In nephrology, dialysis adequacy is the measurement of renal dialysis for the purpose of determining dialysis treatment regime and to better understand the pathophysiology of renal dialysis. It is an area of considerable controversy in nephrology.
In the US, the dominant way of measuring dialysis adequacy in Kt/V and based on the clearance of urea.
Contents |
[edit] Urea
[edit] Comparing normal to ERSD
The normal clearance of urea is approximately 100 ml/min. A patient getting a conventional hemodialysis treatment, without remaining residual function, has a urea clearance of 10-15 ml/min.
[edit] p-Cresol
[edit] beta-2 Microglobulin
Filtration: Ultrafiltration - Countercurrent exchange
Hormones affecting filtration:Antidiuretic hormone (ADH) - Aldosterone - Atrial natriuretic peptide
Endocrine: Renin - Erythropoietin (EPO) - Calcitriol (Active vitamin D) - Prostaglandins
Assessing Renal function / Measures of dialysis: Glomerular filtration rate - Creatinine clearance - Renal clearance ratio - Urea reduction ratio - Kt/V - Standardized Kt/V - Hemodialysis product
Fluid balance - Darrow Yannet diagram - Body water - Interstitial fluid - Extracellular fluid - Intracellular fluid/Cytosol - Plasma - Transcellular fluid - Base excess - Davenport diagram - Anion gap
Bicarbonate buffering system - Respiratory compensation - Renal compensation