Dexetimide
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Dexetimide
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| Systematic (IUPAC) name | |
| 3-(1-benzyl-4-piperidyl)-3-phenyl-piperidine-2,6-dione | |
| Identifiers | |
| CAS number | |
| ATC code | N04 |
| PubChem | |
| Chemical data | |
| Formula | C23H26N2O2 |
| Mol. mass | 362.465 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Dexetimide is a piperidine anticholinergic. It is a muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Dexetimide was discovered at Janssen Pharmaceutica in 1968.
[edit] References
- Dom R, Van Lommel R, Baro F., A quantitative study of neuroleptic-induced extrapyramidal symptoms and their response to dexetimide, a potent and long-acting antiparkinsonian agent, Acta Psychiatr Scand. 1971;47(4):399-410.
- Huygens H, Vereecken JL, Tanghe A., Dexetimide (R 16470) in the control of neuroleptic-induced extrapyramidal side-effects. Its prophylactic value and duration of action, Psychiatr Neurol Neurochir. 1973 Jul-Aug;76(4):251-9.
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