User:Daviddecraene
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Contents |
[edit] Who am I?
Ph. D. Biomedical Sciences.
Expertise in the following fields:
- Signal Transduction
- Carcinogenesis
- Formal Ontology
- Expertise in modeling and management of large-scale Ontologies
Currently employed by Language and Computing.
[edit] Publications
[edit] Biomedical sciences
Decraene D. et al
JID 125(5): 1026-31. 2005.
A low UVB dose, with the potential to trigger a protective p53-dependent gene program, increases the resilience of keratinocytes against future UVB insults.
Decraene D. et al
JID 123(1): 207-12. 2004.
AKT status controls susceptibility of malignant keratinocytes to the early-activated and UVB-induced apoptotic pathway.
Decraene D. et al
JID 122(2): 484-91. 2004.
A synthetic superoxide dismutase/catalase mimetic (EUK-134) inhibits membrane-damage-induced activation of mitogen-activated protein kinase pathways and reduces p53 accumulation in ultraviolet B-exposed primary human keratinocytes.
Decraene D.et al
JBC 277(36): 32587-95. 2002.
Insulin-like growth factor-1-mediated AKT activation postpones the onset of ultraviolet B-induced apoptosis, providing more time for cyclobutane thymine dimer removal in primary human keratinocytes.
Decraene D. et al
J Photochom & Photobiol. 63(1-3):78-83. 2001.
Acute response of human skin to solar radiation: regulation and function of the p53 protein.
Claerhout S., Decraene D.et al
JID, advance online publication. august 2006.
AKT Delays the Early-Activated Apoptotic Pathway in UVB-Irradiated Keratinocytes Via BAD Translocation.
PH.D. Dissertation:
The UVB-response in human skin and its modulation by the proto-oncogenic AKT signaling pathway.
[edit] Ontology
The Methodology behind the Military Health System Conceptual Framework and Core Ontology.
Mariana Casella dos Santos, Christoffel Dhaen, David Decraene, Maria van Gurp, Tom Deray.
CliniComp Terminology Mapping: Methodology
David Decraene, Karen Doyle, Dave Hellman & Mariana Casella dos santos.
