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This is an image of murine CTLA4 (CD152) which is necessary for inhibiting the T cells. It binds to CD28 with a higher affinity than the costimulatory molecules CD80 and CD86. This image is derived from Protein Data Bank data 1DQT which was published by Ostrov et al in 2000. I rendered the image in PyMol myself based on the published pdb file.
For the published pdb, please see: Ostrov, D.A., Shi, W., Schwartz, J.C., Almo, S.C., Nathenson, S.G. Structure of murine CTLA-4 and its role in modulating T cell responsiveness. Science v290 pp.816-819 , 2000.
Description |
Crystal structure of CTLA4 as published in the Protein Data Bank (PDB: 1DQT)
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Source |
Created from PDB 1DQT and rendered by me using Pymol
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Date |
12-10-2006
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Author |
Ramin Herati
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Permission |
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File links
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