Constitutive androstane receptor
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nuclear receptor subfamily 1, group I, member 3
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| Identifiers | |
| Symbol | NR1I3 |
| HUGO | 7969 |
| Entrez | 9970 |
| OMIM | 603881 |
| RefSeq | NM_005122 |
| UniProt | Q4U0F0 |
| Other data | |
| Locus | Chr. 1 q23.3 |
The constitutive androstane receptor (CAR) is a nuclear hormone receptor with activity similar to that seen in other steroid receptors such as estrogen or progesterone but more similar in form to PPAR, LXR and RXR. CAR functions somewhat differently from other steroid receptors and its activity is still being elucidated. It is known to act in concert with PXR to detoxify xenobiotics.
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This biochemistry article is a stub. You can help Wikipedia by expanding it. |
CAP - CAR - CBF - E2F - KlF - Nanog - NF-kB - Oct-4 - P300/CBP - PIT-1 - Rho/Sigma - R-SMAD - Sox2 - Sp1 - STAT (STAT1, STAT3, STAT5)
Basic-helix-loop-helix: AhR - HIF - MYC - MyoD - Myogenin - Twist
Basic leucine zipper: C/EBP - CREB - AP-1
Basic helix-loop-helix leucine zipper: MITF - SREBP
Steroid hormone receptors
Type I: Glucocorticoid - Mineralocorticoid - Sex hormone (Androgen, Estrogen, Progesterone)
Type II: Calcitriol - Retinoid (RAR, RXR) - Thyroid hormone
