Coma

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For other meanings of the word "coma", see the coma (disambiguation).

Name of Symptom/Sign:
**Coma**
*Classifications and external resources*
ICD-10	R40.2
ICD-9	780.01

In medicine, a coma (from the Greek κῶμα koma, meaning deep sleep) is a profound state of unconsciousness. A comatose patient cannot be awakened, fails to respond normally to pain or light, does not have sleep-wake cycles, and does not take voluntary actions. Coma may result from a variety of conditions, including intoxication, metabolic abnormalities, central nervous system diseases, acute neurologic injuries such as stroke, and hypoxia. It may also be deliberately induced by pharmaceutical agents in order to preserve higher brain function following another form of brain trauma.

1 Derivation
2 Distinctive phases of coma
3 Outcome
4 Records
5 Diagnosis and treatment
6 See also
7 References
8 External links

[edit] Derivation

The word coma comes from the Greek God Comas, who was in charge of a sector of the world. Comas was one day walking about the earth when he tripped and fell on a scepter. He fell into a deep sleep and was woken up five hundred years later by a commoner. The commoner was surprised by the longevity of this "man's" sleep and named the coma after Comas.

[edit] Distinctive phases of coma

Within coma itself, there are several categories that describe the severity of impairment. Contrary to popular belief, a patient in a comatose state does not always lay still and quiet. They may talk, walk, and perform other functions that may sometimes appear to be conscious acts, yet are not.

Two scales of measurement frequently used in TBI diagnosis to determine the phase of coma are the Glasgow Coma Scale and the Ranchos Los Amigos Scale. The GCS is a simple 15-point scale used by medical professionals to assess severity of neurologic trauma, and establish a prognosis. The RLAS is a more complex scale that describes up to eight separate levels of coma, and is often used in the first few weeks or months of coma while the patient is under closer observation, and when shifts between levels are more frequent.

[edit] Outcome

There are several levels of coma, through which patients may or may not progress. During the first level of coma, the responsiveness of the brain lessens, normal reflexes are lost, and the patient no longer responds to pain. The patient also can't hear in the normal stage of coma. The chances of recovery depend on the severity of the underlying cause. A deeper coma alone does not necessarily mean a slimmer chance of recovery, because some people in deep coma recover well while others in a so-called milder coma sometimes fail to improve.

The outcome for coma and vegetative state depends on the cause, location, severity and extent of neurological damage: outcomes range from recovery to death. People may emerge from a coma with a combination of physical, intellectual and psychological difficulties that need special attention. Recovery usually occurs gradually, with patients acquiring more and more ability to respond. Some patients never progress beyond very basic responses, but many recover full awareness. Gaining consciousness again is not instant: in the first days, patients are only awake for a few minutes, and duration of time awake gradually increases.

Comas generally last a few days to a few weeks, and rarely last more than 2 to 5 weeks. After this time, some patients gradually come out of the coma, some progress to a vegetative state, and others die. Many patients who have gone into a vegetative state go on to regain a degree of awareness. Others may remain in a vegetative state for years or even decades. Predicted chances of recovery are variable due to different techniques used to measure the extent of neurological damage. All the predictions are based on statistical rates with some level of chance for recovery present: a person with a low chance of recovery may still awaken. Time is the best general predictor of a chance for recovery, with the chances for recovery after 4 months of brain damage induced coma being low (less than 15%), and full recovery being very low. [1] [2]

The most common cause of death for a person in a vegetative state is secondary infection such as pneumonia which can occur in patients who lie still for extended periods.

Occasionally people come out of their comas after long periods of time. One man after nineteen years in a coma spontaneously began speaking and regained awareness of his surroundings. [3]

[edit] Records

According to the Guinness Book of Records, the longest period of time spent in a coma was by Elaine Esposito. She did not wake up after being anaesthetized for an appendectomy on August 6, 1941, at age 6. She died on November 25, 1978 at age 43 years 357 days, having been in a coma for 37 years 111 days.

[edit] Diagnosis and treatment

Diagnosis has the following steps: Medical History, Physical Exam & Neurological Evaluation, Eye Examination, Laboratory Tests, Imaging Studies (CT,MRI), EEG.

The Glasgow Coma Scale is used to quantify the severity of a coma. There are three components to the score: Eye opening response, Verbal response, and Motor response.

In Germany, music therapy is used to attempt to arouse patients from coma.^{[citation needed]}