Talk:Coenzyme A
From Wikipedia, the free encyclopedia
 |
Coenzyme A is within the scope of WikiProject Chemicals, a daughter project of WikiProject Chemistry, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project. | ||
|
Article Grading: The article has not been rated for quality and/or importance yet. Please rate the article and then leave comments here to explain the ratings and/or to identify the strengths and weaknesses of the article.. |
|||
 |
This article is within the scope of the Molecular and Cellular Biology WikiProject. To participate, visit the WikiProject for more information. The current monthly improvement drive is Signal transduction. |
||
| Start | This article has been rated as Start-Class on the assessment scale. |
||
| High | This article is on a subject of High-importance within molecular and cellular biology. | ||
|
Article Grading: The article has been rated for quality and/or importance but has no comments yet. If appropriate, please review the article and then leave comments here to identify the strengths and weaknesses of the article and what work it will need. |
|||
Why is Acetyl CoA called the crossroads compound? what is it relationg to?
"Coenzyme A is very central to the balance between carbohydrate metabolism and fat metabolism. Carbohydrate metabolism needs some CoA for the citric acid cycle to continue, and fat metabolism needs a larger amount of CoA for breaking down fatty acid chains during β-oxidation. Fats can only supply energy by being broken down into small units, and our cells have only one way of doing this: breaking fats down into acetyl-CoA molecules, each of which needs a CoA molecule for its production."
How come the breakdown of fatty acids into acetyl-CoA is a hindrance to the continuance of the citric acid cycle if pyruvate(products of glycoliysis) only enters the Krebs cycle after conversion into acetil CoA? At first sight it seems the breakdown of fatty acids would supply the citric acid cycle with more material. Am I missing some important link or is there an inconsistency in the test?
I'd appreciate an email to remind me when a reply is posted.
Thank You
The role of acetyl-coenzyme A in the catabolic reaction of alcohol (ethanol)
My guess is that acetyl-coenzyme A is made into aceteic acid in the following reaction. Am I correct?
acetyl-CoA + NADH → CoA + NAD+ + CH3COOH
This would be a good thing to include in the article. --Eribro 14:50, 27 April 2006 (UTC)
[edit] stereochemistry
I have been looking at other sources of information for Acetyl CoA and think that the WP page has a different stereochemistry for the alcohol group. See | my blog for other links. In particular I think it differs from ChEBI. Petermr 10:37, 3 September 2006 (UTC)
