Coast Guard cocktail

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A "Coast Guard cocktail" is a prescribed combination of drugs used to combat seasickness. Traditionally the cocktail base is promethazine, an antihistamine that is used specifically to prevent motion sickness. Because of the drowsiness associated with this drug, a stimulant is added to complete the cocktail. Traditionally the stimulant is either ephedrine or pseudoephedrine. There are other combinations of drugs used to prevent seasickness but they are not generally referred to as the "Coast Guard cocktail".


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