Talk:Cholinesterase enzyme
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Concerning merge from acetylcholinesterase: I consciously merged the articles in the reverse direction because acetylcholinesterase is fully dealt with on this page. Moreover, as the current page mentions there are two enzymes referred to as cholinesterase. It would thus be erroneous or misleading at least to redirect cholinesterase to the other article. Notice I left the stub status there. --Phils 17:05, 18 Oct 2004 (UTC)
[edit] External links broken
Removed here, if someone could find the documents in question without page forwarding links, it'd be awesome. Otherwise will do later hopefully.
- Study showing magnolia oil as an acetylcholinesterase inhibitor.
- Cholinesterase inhibitors might alleviate methamphetamine-induced delusions, hallucinations and cognitive impairment, while reducing craving and addiction
—The preceding unsigned comment was added by Tom Meakin (talk • contribs) 09:54, 31 January 2007 (UTC).
[edit] Cholinesterase inhibitor discoverer
Revision as of 06:38, 22 August 2005 by 211.30.120.226 stated that
Cholinesterase inhibitors were discovered by Professor Cardillo of Sydney University, Australia.
On August 23rd 2005, User:Jfdwolff removed that part and commented:
Strychnine has been around for much longer
Although I'm unable to confirm the first statement, I know for sure that the counterargument doesn't stand. Even though the manifestations of a strychnine poisoning resemble that of a cholinesterase inhibitor massive overdose in that both may produce myoclonic or tetanic convulsion, strychnine is not a cholinesterase inhibitor.
Strychnine works by blocking the release of glycine from inhibitory interneurons in the spinal cord. This increases reflex excitability and result in convulsion.
Ref: Rang HP, Dale MM, Ritter JM. Pharmacology ISBN 0-443-05974-8
If someone can ascertain that a Professor Cardillo did discover cholinesterase inhibitor, please add it to the text and state your source.
Benoitduhaime 05:24, 9 October 2005 (UTC)
