Cholesterol side-chain cleavage enzyme

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cytochrome P450, family 11, subfamily A, polypeptide 1
Identifiers
Symbol CYP11A1 CYP11A
HUGO 2590
Entrez 1583
OMIM 118485
RefSeq NM_000781
UniProt P05108
Other data
EC number 1.14.15.67
Locus Chr. 15 q23-q24

P450 scc (or 20,22-Desmolase) is an enzyme associated with the conversion of cholesterol to pregnenolone. The terminology "Desmolase" is becoming outdated and the enzyme is now more commonly referred to as P450scc.

The "scc" refers to side chain cleavage.

Contents

[edit] Steroid hormone synthesis

Steroid hormone synthesis
Steroid hormone synthesis

[edit] See also

[edit] Additional images

Cholesterol

Pregnenolone

[edit] External links

 This biochemistry article is a stub. You can help Wikipedia by expanding it.
v • d • e
Cytochrome P450, oxygenases: steroid hydroxylases (EC 1.14)

Side-chain cleavage - 21-hydroxylase - 18-hydroxylase - 11-beta-hydroxylase

17-alpha-hydroxylase - Aromatase

CYP27A1

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Enzymes: multienzyme complexes

Aspartate carbamoyltransferase - Cholesterol side-chain cleavage enzyme - Cytochrome b6f complex - Electron transport chain - Fatty acid synthetase complex - Oxoglutarate dehydrogenase - Phosphoenolpyruvate sugar phosphotransferase system - Photosynthetic reaction center complex proteins - Photosystem - Polyketide synthase - Pyruvate dehydrogenase complex (E1, E2, E3) - Sucrase-isomaltase complex - Tryptophan synthase

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