Cholecystokinin receptor
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cholecystokinin A receptor
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| Identifiers | |
| Symbol | CCKAR |
| HUGO | 1570 |
| Entrez | 886 |
| OMIM | 118444 |
| RefSeq | NM_000730 |
| UniProt | P32238 |
| Other data | |
| Locus | Chr. 4 p15.2-p15.1 |
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cholecystokinin B receptor
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| Identifiers | |
| Symbol | CCKBR |
| HUGO | 1571 |
| Entrez | 887 |
| OMIM | 118445 |
| RefSeq | NM_176875 |
| UniProt | P32239 |
| Other data | |
| Locus | Chr. 11 p15.4 |
Cholecystokinin receptors or CCK receptors are a group of G-protein coupled receptors. There are two different subtypes CCK1 and CCK2. They are ~50% homologous. The CCK1 receptor binds mostly to Cholecystokinin while CCK2 also binds to gastrin. They are mostly involved in various digestive functions like gastrin-stimulated gastric acid secretion, gastric emptying and gut motility. In the brain, CCK functions as a neuropeptide and CCK receptors are involved in nociception, anxiety, memory and hunger.
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Adenosine - Adrenergic - Angiotensin - Bradykinin - Calcitonin - Cannabinoid - Chemokine - Cholecystokinin - Corticotropin-releasing hormone - C5A - Dopamine - Endothelin - FSH-receptor - GABA B - Galanin - Glucagon - Gonadotropin-releasing hormone - Histamine (H1, H2, H3, H4) - Luteinizing hormone/choriogonadotropin - Melanocortin (MC1R, MC2R) - Melatonin - Metabotropic glutamate - Muscarinic acetylcholine - Neurotensin - Olfactory - Opioid (Delta, Kappa, Mu, Sigma, Nociceptin) - Parathyroid hormone - Purinergics (P2Y) - Trace amine-associated - Secretin - Serotonin, all but 5-HT3 (5-HT2A)
CRH - FSH - LHRH - TRH - Somatostatin
Vasopressin (1A, 1B, 2) - Oxytocin - LHCG - GH - Prolactin - TSH
Angiotensin - Atrial natriuretic factor - Bradykinin - Calcitonin - Calcitonin gene-related peptide - Cholecystokinin - Galanin - Neuropeptide Y - Neurotensin - Opioid (Delta, Kappa, Mu, Sigma, Nociceptin) - Tachykinin - VIP
