Chlortalidone


Chlortalidone
Systematic (IUPAC) name
2-chloro-5-(1-hydroxy-3-oxo-1,2-dihydroisoindol-1-yl)- benzenesulfonamide
Identifiers
CAS number	77-36-1
ATC code	C03BA04
PubChem	2732
DrugBank	APRD00127
Chemical data
Formula	C₁₄H₁₁Cl N₂O₄S
Mol. mass	338.767 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	75%
Metabolism	?
Half life	40 hours
Excretion	Renal
Therapeutic considerations
Pregnancy cat.	C (Au), B (U.S.)
Legal status	POM (UK)
Routes	Oral

Chlortalidone (formerly spelt chlorthalidone in the UK) is a thiazide diuretic, used to treat hypertension.

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

v • d • e Antihypertensives (C02) and diuretics (C03)
Antiadrenergic agents (including alpha)	Clonidine, Doxazosin, Guanethidine, Guanfacine, Lofexidine,Mecamylamine, Methyldopa, Moxonidine, Prazosin, Rescinnamine, Reserpine
Vasodilators	Diazoxide, Hydralazine, Minoxidil, Nitroprusside, Phentolamine
Other antihypertensives	Bosentan, Ketanserin
Low ceiling diuretics	Bendroflumethiazide, Chlorothiazide, Chlortalidone, Hydrochlorothiazide, Indapamide, Quinethazone, Mersalyl, Metolazone, Theobromine, Cicletanine
High ceiling diuretics	Bumetanide, Furosemide, Torasemide
Potassium-sparing diuretics	Amiloride, Eplerenone, Spironolactone, Triamterene