Cefpiramide
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Cefpiramide
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| Systematic (IUPAC) name | |
| (6R)-7-{[(2R)-2-(4-hydroxyphenyl)-2-[(6-methyl- 4-oxo-1H-pyridine-3-carbonyl)amino]acetyl]amino}- 3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo- 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
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| Identifiers | |
| CAS number | |
| ATC code | J01 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C25H24N8O7S2 |
| Mol. mass | 612.64 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Protein binding | 93% to 99.3% |
| Metabolism | ? |
| Half life | 4.44 hours |
| Excretion | Renal and fecal |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | Intravenous, intramuscular |
Cefpiramide is a third-generation cephalosporin antibiotic.
[edit] External links
- Wang H, Yu Y, Xie X, Wang C, Zhang Y, Yuan Y, Zhang X, Liu J, Wang P, Chen M (2000). "In-vitro antibacterial activities of cefpiramide and other broad-spectrum antibiotics against 440 clinical isolates in China.". J Infect Chemother 6 (2): 81-5. PMID 11810540.
- Iakovlev V, Vishnevskiĭ V, Khlebnikov E, Khadin I, Plavlova M, Elagina L, Izotova G (1995). "[Cefpiramide (Tamicin) in the treatment of purulent complications of abdominal surgery]". Antibiot Khimioter 40 (9): 30-4. PMID 8651827.
- Sampi K, Hattori M (1992). "[Comparative study of cefpiramide + amikacin versus piperacillin + amikacin in granulocytopenic patients: a randomized, prospective study]". Gan To Kagaku Ryoho 19 (9): 1315-20. PMID 1503486.
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This antibiotic-related article is a stub. You can help Wikipedia by expanding it. |
| Cephalosporin Antibiotics (J01D) | |
|---|---|
| First Generation | Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefalonium, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazaflur, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole |
| Second Generation | Cefaclor, Cefamandole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime, Cefuzonam |
| Third Generation | Cefcapene, Cefdaloxime, Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpimizole, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Cefteram, Ceftibuten, Ceftiofur, Ceftiolene, Ceftizoxime, Ceftriaxone, Latamoxef |
| Fourth Generation | Cefclidine, Cefepime, Cefetecol,Cefluprenam, Cefoselis, Cefozopran, Cefpirome, Cefquinome |
