Cefacetrile
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Cefacetrile
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Systematic (IUPAC) name | |
(6R,7R)-3-(acetyloxymethyl)-7-[(2-cyanoacetyl)amino]- 8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2- carboxylic acid |
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Identifiers | |
CAS number | |
ATC code | J01 |
PubChem | |
Chemical data | |
Formula | C13H13N3O6S |
Mol. mass | 339.325 g/mol |
Pharmacokinetic data | |
Bioavailability | ? |
Protein binding | 23 to 38% |
Metabolism | ? |
Half life | 1.2 hours |
Excretion | Renal (72%) |
Therapeutic considerations | |
Pregnancy cat. |
? |
Legal status | |
Routes | Intravenous, intramuscular |
Cefacetrile (INN, also spelled cephacetrile) is a broad-spectrum first generation cephalosporin antibiotic effective in Gram-positive and Gram-negative bacterial infections. It is a bacteriostatic antibiotic. Cefacetrile is marketed under the tradenames Celospor®, Celtol®, and Cristacef®.
Cephalosporin Antibiotics (J01D) | |
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First Generation | Cefacetrile, Cefadroxil, Cefalexin, Cefaloglycin, Cefalonium, Cefaloridine, Cefalotin, Cefapirin, Cefatrizine, Cefazaflur, Cefazedone, Cefazolin, Cefradine, Cefroxadine, Ceftezole |
Second Generation | Cefaclor, Cefamandole, Cefonicid, Ceforanide, Cefotiam, Cefprozil, Cefuroxime, Cefuzonam |
Third Generation | Cefcapene, Cefdaloxime, Cefdinir, Cefditoren, Cefetamet, Cefixime, Cefmenoxime, Cefodizime, Cefoperazone, Cefotaxime, Cefpimizole, Cefpiramide, Cefpodoxime, Cefsulodin, Ceftazidime, Cefteram, Ceftibuten, Ceftiofur, Ceftiolene, Ceftizoxime, Ceftriaxone, Latamoxef |
Fourth Generation | Cefclidine, Cefepime, Cefetecol,Cefluprenam, Cefoselis, Cefozopran, Cefpirome, Cefquinome |