CD133
From Wikipedia, the free encyclopedia
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prominin 1
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| Identifiers | |
| Symbol | PROM1 PROML1, CD133 |
| HUGO | 9454 |
| Entrez | 8842 |
| OMIM | 604365 |
| RefSeq | NM_006017 |
| UniProt | O43490 |
| Other data | |
| Locus | Chr. 4 p15 |
CD133 is a glycoprotein also known in humans and rodents as Prominin 1 (PROM1).[1] It is the founding member of pentaspan transmembrane glycoproteins (5-transmembrane, 5-TM), which specifically localizes to cellular protrusions. CD133 is expressed in hematopoietic stem cells, glioblastomas, neuronal and glial stem cells and some other cell types.[2][3]
[edit] References
- ^ Corbeil D, Fargeas C, Huttner W (2001). "Rat prominin, like its mouse and human orthologues, is a pentaspan membrane glycoprotein". Biochem Biophys Res Commun 285 (4): 939-44. PMID 11467842.
- ^ Corbeil D, Röper K, Hellwig A, Tavian M, Miraglia S, Watt S, Simmons P, Peault B, Buck D, Huttner W (2000). "The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions". J Biol Chem 275 (8): 5512-20. PMID 10681530.
- ^ Shmelkov S, St Clair R, Lyden D, Rafii S (2005). "AC133/CD133/Prominin-1". Int J Biochem Cell Biol 37 (4): 715-9. PMID 15694831.
CD1 - CD1d - CD2 - CD3 - CD4 - CD8 - CD11a - CD11b - CD11c - CD14 - CD15 - CD18 - CD19 - CD20 - CD22 - CD23 - CD24 - CD25 - CD26 - CD28 - CD29 - CD30 - CD31 - CD32 - CD33 - CD34 - CD35 - CD36 - CD38 - CD40 - CD43 - CD44 - CD45 - CD46 - CD49a - CD49b - CD49c - CD49d - CD52 - CD54 - CD56 - CD62E - CD62L - CD62P - CD66e - CD68 - CD70 - CD71 - CD72 - CD79 - CD80 - CD86 - CD90 - CD94 - CD95 - CD98 - CD106 - CD117 - CD122 - CD130 - CD132 - CD133 - CD134 - CD141 - CD142 - CD143 - CD146 - CD147 - CD152 - CD153 - CD154 - CD155 - CD164 - CD184 - CD169 - CD206 - CD209 - CD278
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