Carboxyfluorescein

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Carboxyfluorescein
Common name 6-FAM
Systematic name 2',7'-bis(2-Carboxyethyl)-5(6)-carboxyfluorescein
Other names
Chemical formula C27H20O11
FW 520.5
mp
CAS number 85138-49-4

Carboxyfluorescein is a fluorescent dye with an excitation and emission of 492/517 nm, respectively. It is commonly used as a tracer agent. The dye is membrane-impermeant and can be loaded into cells by microinjection or scrape loading.[1] It can be incoporated into liposomes, and allow for the tracking of liposomes as they pass through the body. In addition, Carboxyfluorescein has been used to track division of cells.[2]

[edit] Notes

  1. ^ Molecular Imaging Products Company (2005-08-26). 5-(and-6)-Carboxyfluorescein (5-(and-6)- FAM,mixed isomer) 100mg. Retrieved on August 26, 2006.
  2. ^ Parish, Christopher (1999-12). Fluorescent dyes for lymphocyte migration and proliferation studies. Immunology and Cell Biology. Blackwell Synergy. Retrieved on August 26, 2006.