Brimonidine
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Brimonidine
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| Systematic (IUPAC) name | |
| 5-bromo-N- (4,5-dihydro-1H-imidazol-2-yl) quinoxalin-6-amine | |
| Identifiers | |
| CAS number | |
| ATC code | S01 |
| PubChem | |
| DrugBank | |
| Chemical data | |
| Formula | C11H10BrN5 |
| Mol. mass | 292.135 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | liver primarily |
| Half life | 3 hours |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
B |
| Legal status |
unknown |
| Routes | Ocular, 1 gtt |
Brimonidine (bri-MOE-ni-deen ) is a drug used to treat glaucoma. It acts via decreasing aqueous humor synthesis.
Brimonidine is an alpha2 receptor agonist.
[edit] Side effects
- Conjunctivitis
- Conjunctival hyperemia
- Ocular pruritus
- Ocular burning
- Conjunctival follicles
- Hypertension
- Dry mouth
- Visual changes
- Somnolence
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| Sympathomimetics | Apraclonidine, Brimonidine, Clonidine, Dipivefrine, Epinephrine |
| Parasympathomimetics | Aceclidine, Acetylcholine, Carbachol, Demecarium, Echothiophate, Fluostigmine, Neostigmine, Paraoxon, Physostigmine, Pilocarpine |
| Carbonic anhydrase inhibitors | Acetazolamide, Brinzolamide, Diclofenamide, Dorzolamide, Methazolamide |
| Beta blocking agents | Befunolol, Betaxolol, Carteolol, Levobunolol, Metipranolol, Timolol |
| Prostaglandin analogues | Bimatoprost, Latanoprost, Travoprost, Unoprostone |
| Other agents | Dapiprazole, Guanethidine |
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