Bradykinin receptor
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bradykinin receptor B1
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| Identifiers | |
| Symbol | BDKRB1 |
| HUGO | 1029 |
| Entrez | 623 |
| OMIM | 600337 |
| RefSeq | NM_000710 |
| UniProt | P46663 |
| Other data | |
| Locus | Chr. 14 q32.1-32.2 |
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bradykinin receptor B2
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| Identifiers | |
| Symbol | BDKRB2 |
| HUGO | 1030 |
| Entrez | 624 |
| OMIM | 113503 |
| RefSeq | NM_000623 |
| UniProt | P30411 |
| Other data | |
| Locus | Chr. 14 q32.1-32.2 |
Bradykinin, along with kallidin signals through the B2 receptor which is ubiquitously and constitutively expressed in healthy tissues.
The B2 receptor is a G protein-coupled receptor and stimulates phospholipase C to increase intracellular free calcium, inhibits adenylate cyclase and stimulates the mitogen-activated protein kinase pathways.
[edit] External links
Adenosine - Adrenergic - Angiotensin - Bradykinin - Calcitonin - Cannabinoid - Chemokine - Cholecystokinin - Corticotropin-releasing hormone - C5A - Dopamine - Endothelin - FSH-receptor - GABA B - Galanin - Glucagon - Gonadotropin-releasing hormone - Histamine (H1, H2, H3, H4) - Luteinizing hormone/choriogonadotropin - Melanocortin (MC1R, MC2R) - Melatonin - Metabotropic glutamate - Muscarinic acetylcholine - Neurotensin - Olfactory - Opioid (Delta, Kappa, Mu, Sigma, Nociceptin) - Parathyroid hormone - Purinergics (P2Y) - Trace amine-associated - Secretin - Serotonin, all but 5-HT3 (5-HT2A)
CRH - FSH - LHRH - TRH - Somatostatin
Vasopressin (1A, 1B, 2) - Oxytocin - LHCG - GH - Prolactin - TSH
Angiotensin - Atrial natriuretic factor - Bradykinin - Calcitonin - Calcitonin gene-related peptide - Cholecystokinin - Galanin - Neuropeptide Y - Neurotensin - Opioid (Delta, Kappa, Mu, Sigma, Nociceptin) - Tachykinin - VIP
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