Blood island

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Blood island
Gray's	subject #135 506
Dorlands/Elsevier	i_13/12460968

Blood islands are structures in the developing embryo which lead to many different parts of the circulatory system.

They primarily derive from plexuses formed from angioblasts. Within them, vacuoles appear through liquefaction of the central part of the syncytium into plasma.

The lumen of the blood vessels thus formed is probably intracellular.

The flattened cells at the periphery form the endothelium.

The nucleated red blood corpuscles develop either from small masses of the original angioblast left attached to the inner wall of the lumen or directly from the flat endothelial cells.

In either case the syncytial mass thus formed projects from and is attached to the wall of the vessel.

Such a mass is known as a blood island and hemoglobin gradually accumulates within it.

Later the cells on the surface round up, giving the mass a mulberry-like appearance.

Then the red blood cells break loose and are carried away in the plasma.

Such free blood cells continue to divide.

Blood islands have been seen in the area vasculosa in the omphalomesenteric vein and arteries, and in the dorsal aorta.

[edit] External links

"Development of the vascular system", at brown.edu

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Mammalian development of embryo and development of fetus (some dates are approximate - see Carnegie stages)