Bisoprolol

From Wikipedia, the free encyclopedia

Bisoprolol
Systematic (IUPAC) name
1-[4-[2-(1-methylethoxy)ethoxymethyl]
phenoxy]-3-(1-methylethylamino)propan-2-ol
Identifiers
CAS number 66722-44-9
ATC code C07AB07
PubChem 2405
DrugBank APRD00257
Chemical data
Formula C18H31NO4 
Mol. mass 325.443 g/mol
Pharmacokinetic data
Bioavailability >90%
Metabolism Hepatic
Half life 9-12hours
Excretion Renal
Therapeutic considerations
Pregnancy cat.

C(AU) C(US)

Legal status

Prescription only

Routes oral

Bisoprolol is a drug belonging to the group of beta blockers, a class of drugs used primarily in cardiovascular diseases.

[edit] Indications

Bisoprolol can be used to treat cardiovascular diseases such as hypertension, coronary heart disease, arrhythmias, and treatment of myocardial infarction after the acute event. Patients with compensated congestive heart failure may be treated with Bisoprolol as a comedication (usually together with an ACE inhibitor, a diuretic and a digitalis-glycosid, if indicated). In patients with congestive heart failure, it reduces the need for and the consumption of oxygen of the heart muscle. It is very important to start with low doses, as bisoprolol reduces also the muscular power of the heart, which is an undesired effect in congestive heart failure.

The drug is also used to treat other conditions, including dysautonomia, anxiety and hyperthyroidism (overfunction of the thyroid gland).