Talk:Biologics

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sorry wrong entry : Raptiva and Amevive are not anti-TNF alphas.

AMEVIVE® interferes with lymphocyte activation by specifically binding to the lymphocyte antigen, CD2, and inhibiting LFA-3/CD2 interaction.

RAPTIVA binds to CD11a, the subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes, and decreases cell surface expression of CD11a. RAPTIVA inhibits the binding of LFA-1 to intercellular adhesion molecule-1 (ICAM-1), thereby inhibiting the adhesion of leukocytes to other cell types. Interaction between LFA-1 and ICAM-1 contributes to the initiation and maintenance of multiple processes, including activation of T lymphocytes, adhesion of T lymphocytes to endothelial cells, and migration of T lymphocytes to sites of inflammation including psoriatic skin.

Source = label information

other wrong entry : biologicals are not mainly used in rhumatoid arthritis. biologicals are growth hormone, insuline, interferons, etc.. used in various indications —The preceding unsigned comment was added by Nathanael Bar-Aur L. (talk • contribs) 15:43, 3 May 2006 (UTC).

Abatacept is another biologic that should be added to this list. —The preceding unsigned comment was added by 70.91.54.158 (talk • contribs) 15:19, 28 July 2006 (UTC).