Portal:Biology/Previous biographies

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This is a list of featured biographies from the Biology portal, sorted in reverse-chronological order.

Contents

[edit] 2006-10-16

Rosalind Elsie Franklin (25 July 192016 April 1958) was a British physical chemist and crystallographer who made important contributions to the understanding of the fine structures of DNA, viruses, coal and graphite. Franklin is best known for her contribution to the discovery of the structure of DNA in 1953. In the years following, she led pioneering work on the tobacco mosaic and polio viruses. She died in 1958 of cancer of the ovary.


[edit] 2006-08-16

Barbara McClintock (June 16, 1902September 2, 1992) was a pioneering American scientist and one of the world's most distinguished cytogeneticists. McClintock received her PhD in botany from Cornell University in 1927, where she was a leader in the development of maize cytogenetics. The field remained the focus of her research for the rest of her career. From the late 1920s, McClintock studied chromosomes and how they change during reproduction in maize. She developed the technique to visualize maize chromosomes and used microscopic analysis to demonstrate many fundamental genetic ideas, including genetic recombination by crossing-over during meiosis—a mechanism by which chromosomes exchange information. She produced the first genetic map for maize, linking regions of the chromosome with physical traits, and demonstrated the role of the telomere and centromere, regions of the chromosome that are important in the conservation of genetic information. She was recognized amongst the best in the field, awarded prestigious fellowships and elected a member of the National Academy of Sciences in 1944.

During the 1940s and 1950s, McClintock discovered transposition and used it to show how genes are responsible for turning physical characteristics on or off. She developed theories to explain the repression or expression of genetic information from one generation of maize plants to the next. Encountering skepticism of her research and its implications, she stopped publishing her data in 1953. Later, she made an extensive study of the cytogenetics and ethnobotany of maize races from South America. McClintock's research became well understood in the 1960s and 1970s, as researchers demonstrated the mechanisms of genetic change and genetic regulation that she had demonstrated in her maize research in the 1940s and 1950s. Awards and recognition of her contributions to the field followed, including the Nobel Prize in Physiology or Medicine awarded to her in 1983 for the discovery of genetic transposition; to date, she has been the first and only woman to receive an unshared Nobel Prize in that category.

[edit] 2006-07-26

Heinrich Hermann Robert Koch (December 11, 1843May 27, 1910) was a German physician. He became famous for the discovery of the anthrax bacillus (1877), the tuberculosis bacillus (1882) and the cholera bacillus (1883) and for his development of Koch's postulates. He was awarded the Nobel Prize in Physiology or Medicine for his tuberculosis findings in 1905. He is considered one of the founders of bacteriology.

His work on tuberculosis, for which he was awarded a Nobel Prize, provided the intellectual framework that allowed subsequent researchers to identify causal agents of disease - Koch's postulates.

After Koch's success the quality of his own research declined (especially with the fiasco over his ineffective TB cure "tuberculin"), although his pupils found the organisms responsible for diphtheria, typhoid, pneumonia, gonorrhoea, cerebrospinal meningitis, leprosy, bubonic plague, tetanus, and syphilis, among others, by using his methods.

[edit] July 11, 2006

George Ledyard Stebbins, Jr. (January 6, 1906January 19, 2000) was an American botanist and geneticist who is widely regarded as one of the leading evolutionary biologists and botanists of the 20th century. Stebbins received his PhD in botany from Harvard University in 1931. He went on to the University of California, Berkeley where his work with E. B. Babcock on the genetic evolution of plant species and his association with a group of evolutionary biologists known as the Bay Area Biosystematists, led him to develop a comprehensive synthesis of plant evolution. His most important publication in this regard was Variation and Evolution in Plants, which combined genetics and Darwin's theory of natural selection, and is considered to be a major contribution to modern evolutionary synthesis.

From 1950, Stebbins was instrumental in the establishment of the Department of Genetics at the University of California, Davis. He was active in numerous organizations involved in the promotion of evolution, and science more generally, and was elected to the National Academy of Science. He was also involved in the development of evolution-based science programs for Californian high schools, and the conservation of rare plants in that state.

[edit] May 19, 2006

Lynn Margulis (1938 —) is a biologist and University Professor at the University of Massachusetts Amherst. She is best-known for her theory on eukaryotic organelle genesis, the endosymbiotic theory, which is now accepted in the mainstream as the explanation for how certain organelles were formed.

In 1966 Margulis wrote a theoretical paper entitled The Origin of Mitosing Eukaryotic Cells. The paper is considered a landmark in modern endosymbiotic theory. Margulis's endosymbiotic theory formulation is the first to rely on direct microbiological observations (as opposed to paleontological or zoological observations which were previously the norm for new works in evolutionary biology). The paper was initially heavily rejected, as symbiosis theories had been dismissed by mainstream biology at the time. Despite constant criticism of her ideas for decades, Margulis is famous for her tenacity in pushing her theory forward, despite the opposition she faced at the time.

The underlying theme of endosymbiotic theory, as formulated in 1966, was interdependence and cooperative existence of multiple prokaryotic (single celled) organisms; one organism engulfed another, yet both survived and eventually evolved over millions of years into eukaryotic cells. Her 1970 book, Origin of Eukaryotic Cells, discusses her early work pertaining to this organelle genesis theory in detail. Currently, her endosymbiotic theory is recognized as the key method by which some organelles have arisen (see endosymbiotic theory for a discussion) and is widely accepted by mainstream scientifics. The endosymbiotic theory of organogenesis was actually proven in the 1980s, when the genetic material of mitochondria and chloroplasts was found to be different from that of nuclear DNA.

[edit] April 10, 2006

Gregor Johann Mendel

Gregor Mendel (1822–1884) was an Austrian monk who is often called the "father of genetics" for his study of the inheritance of traits in pea plants. Mendel showed that there was particular inheritance of traits according to his laws of inheritance. The significance of Mendel's work was not recognized until the turn of the 20th century.

It was not until the early 20th century that the importance of his ideas was realized. In 1900, his work was rediscovered by Hugo de Vries, Carl Correns, and Erich von Tschermak. His results were quickly replicated, and genetic linkage quickly worked out. Biologists flocked to the theory, as while it was not yet applicable to many phenomena, it sought to give a genotypic understanding of heredity which they felt was lacking in previous studies of heredity which focused on phenotypic approaches. Most prominent of these latter approaches was the biometric school of Karl Pearson and W.F.R. Weldon, which was based heavily on statistical studies of phenotype variation. The strongest opposition to this school came from William Bateson, who perhaps did the most in the early days of publicizing the benefits of Mendel's theory (the word "genetics", and much of the discipline's other terminology, originated with Bateson). This debate between the biometricians and the Mendelians was extremely vigorous in the first two decades of the twentieth century, with the biometricians claiming statistical and mathematical rigor, while the Mendelians claimed a better understanding of biology. In the end, the two approaches were synthesized as the modern synthesis of evolutionary biology, especially by work conducted by Ronald Fisher in 1918.

[edit] March 8, 2006

Thomas Huxley

Thomas Huxley (1825 – 1895) was a British biologist known as "Darwin's Bulldog" for his defence of Charles Darwin's theory of evolution.

His scientific debates against Richard Owen demonstrated that there were close similarities between the cerebral anatomy of humans and gorillas. Huxley did not accept many of Charles Darwin's ideas, such as gradualism, and was more interested in advocating a materialist professional science than in defending natural selection.

Thomas Huxley coined the term "agnosticism" to describe his stance on religious belief (see Thomas Henry Huxley and agnosticism). He is credited with inventing the concept of "biogenesis", a theory stating that all cells arise from other cells, and also "abiogenesis," describing the generation of life from non-living matter.

[edit] March 2, 2006

Thomas Malthus

Ernst Haeckel (1834 – 1919) was an eminent German biologist and philosopher who promoted Charles Darwin's work in Germany. Haeckel was a zoologist, an accomplished artist and illustrator, and later a professor of comparative anatomy. He was one of the first to consider psychology as a branch of physiology. He also proposed many now ubiquitous terms including "phylum" and "ecology." His chief interests lay in evolution and life development processes in general, including development of nonrandom form, which culminated in the beautifully illustrated Kunstformen der Natur (Art forms of nature).

Haeckel advanced the "recapitulation theory" which proposed a link between ontogeny (development of form) and phylogeny (evolutionary descent), summed up in the phrase "ontogeny recapitulates phylogeny". He supported the theory with embryo drawings that have since been shown to be inaccurate, and the theory is no longer generally accepted.

[edit] February 23, 2006

Thomas Malthus

Thomas Malthus, (1766 – 1834) was an English demographer and political economist best known for his pessimistic but highly influential views on population growth. Malthus' Principle of Population was based on the idea that population, if unchecked, increases at an exponential rate (i.e. 2, 4, 8, 16, 32, 64, 128, etc.) whereas the food supply grows at a linear rate (i.e. 1, 2, 3, 4, 5, 6, 7, 8, etc.). Only natural causes (eg. accidents and old age), misery (war, pestilence, and above all famine), moral restraint and vice (which for Malthus included infanticide, murder, contraception and homosexuality) could check excessive population growth; otherwise, the end result would be catastrophe. Malthus' ideas figured prominently in the work of Charles Darwin, who partially based his theory of evolution on the idea of competition of species for limited resources.