Benzethonium chloride

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Benzethonium chloride
Systematic (IUPAC) name
benzyl-dimethyl-[2-[2-[4-
(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]
azanium chloride
Identifiers
CAS number 121-54-0
ATC code D08AJ58
PubChem 8478
Chemical data
Formula C27H42ClNO2 
Mol. mass 448.081 g/mol
SMILES search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status

OTC(US)

Routes Topical

Benzethonium chloride is a synthetic quaternary ammonium, surfactant, antiseptic, and anti-infective compound used as a topical antimicrobial agent in cosmetics and personal care products like anti-itch ointments and antibacterial moist towelettes and wipes. Benzothonium chloride is also used is the food industry as a disinfectant and preservative. [1]. It has the appearance of an odorless white crystalline hygroscopic powder and has a melting point of 162-164 °C. The compound is moderately soluble in water and is toxic orally because it may cause failure in neuromuscular transmission as a result of pathological disturbance at the myoneural junction.[2]

It is available under trade names salanine, BZT, diapp, quatrachlor, polymine d, phemithyn, antiseptol, disilyn, phermerol, and others. [3]

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