BEACOPP

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BEACOPP is a chemotherapy regimen for treatment of Hodgkin's lymphoma in Stages > II. Patients typically receive treatment in cycles of 21 days with no drugs given on days 16-21. There also exists a more intensive regimen with cycles of 14 days. Usually a therapy consists of eight, sometimes six cycles. In some countries BEACOPP still is experimental, in others (eg. Germany and Austria) it is a standard therapy.

m² = body surface

i.v.=intravenous

BEACOPP basic:

(C)yclophosphamide	650 mg/m²	(i.v.)	day 1
(A)driamycin	25 mg/m²	i.v.	day 1
(E)toposide	100 mg/m²	i.v.	day 1-3
Vincristin(=(O)ncovin)	1,4 mg/m² (max 2 mg)	i.v.	day 8
(B)leomycin	10 mg/m²	i.v.	day 8
(P)rocarbazine	100 mg/m²	orally	day 1-7
(P)rednisone	40 mg/m²	orally	day 1-14

BEACOPP escalated:

Cyclophosphamide	1250 mg/m² KO/day	i.v.	day 1
Adriamycin	35 mg/m²	i.v.	day 1
Etoposide	200 mg/m²	i.v.	day 1-3
Vincristine	1,4 mg/m² (max 2 mg)	i.v.	day 8
Bleomycin	10 mg/m²	i.v.	day 8
Procarbazine	100 mg/m²	orally	day 1-7
Prednisone	40 mg/m²	orally	day 1-14