Bcl-2 homologous antagonist killer

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The Bcl-2 homologous antagonist/killer (BAK) protein is a pro-apoptotic member of the Bcl-2 gene family which is involved in initiating apoptosis. It has a relative molecular weight of 23,400 and contain 211-amino acids. Dysregulation of the BAK gene has been implicated in human gastrointestinal cancers, indicating that the gene plays a part in the pathogenesis of some cancers[1].

[edit] See also

[edit] References

  1. ^ Qiang-Song Tong, et al. (2004). "BAK overexpression mediates p53-independent apoptosis inducing effects on human gastric cancer cells". BMC Cancer 4 (33). 
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