Aurora B kinase
From Wikipedia, the free encyclopedia
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aurora kinase B
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| Identifiers | |
| Symbol | AURKB STK12 |
| HUGO | 11390 |
| Entrez | 9212 |
| OMIM | 604970 |
| RefSeq | NM_004217 |
| UniProt | Q96GD4 |
| Other data | |
| EC number | 2.7.1.37 |
| Locus | Chr. 17 p13.1 |
Aurora B kinase functions in the attachment of the mitotic spindle to the centromere.
In cancerous cells, over expression of these enzymes cause unequal distribution of genetic information creating aneuploidy cells, a hallmark of cancer.
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AMP-activated - Aurora (A, B) - Beta adrenergic receptor - Bone morphogenetic protein receptors - c-Raf - Ca2+/calmodulin-dependent (Myosin light-chain) - CDKL5 - Cyclin-dependent - EIF-2 - GSK-3 - Mammalian target of rapamycin - Mitogen-activated/MAP2K/MAP3K (Extracellular signal-regulated, C-Jun N-terminal, P38 mitogen-activated protein) - Phosphorylase - Rhodopsin
Protein kinase A - Protein kinase B - Protein kinase C - Protein kinase G
