At3g19720

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At3g19720.1

Model of N-terminal domain of Arc5
Gene code: SWISS-PROT code: Q3EB39
Structure: molecular structure
Recent publications: role in plant pathologies, gene knockout phenotypes
protein type: Hemoprotein
Functions: chloroplast division
Domains: globin
Diseases: chloroplast hypertrophy
Taxa expressing: many metazoan phyla, Archaea?, protozoan/eubacterial?
Cell types: leaf cells
Subcellular localization: cytoplasm
covalent modifications glycation?
Other names: Arc5-like proteins in microorganisms
Molecular interactions PDV1 and PDV2
related articles: X-ray crystallography, Secondary structure

In the plant Arabidopsis thaliana, At3g19720 is a gene locus for which there are two gene models, At3g19720.1 and a splice variant At3g19720.2. The protein is also known as Arc5, which stands for "Accumulation and replication of chloroplast 5".

Contents

[edit] Properties

Arc5 has 778 amino acids and an estimated molecular weight of 87172 Da. It is a relatively neutral protein, with a pI of 6.7.

[edit] Function

This protein is involved in chloroplast division. It is being studied by people interested in chloroplast morphogenesis.

[edit] Domain structure

The N-terminal domain is homologous to a dynamin-GTPase domain, corresponding to InterPro family IPR001401 and Pfam family PF00350.

[edit] Knockout phenotype

Mutants exhibit fewer and larger chloroplasts.

[edit] Localization and expression

Arc5 is a cytosolic protein, but localizes to the outer ring separating the two daughter chloroplasts during chloroplast division.

[edit] Interactions

Arc5 appears to be recruited to the chloroplast division site by two proteins PDV1 and PDV2.

[edit] References

    [edit] Further reading

    [edit] General database links