Aspartate transaminase

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Aspartate aminotransferase

Aspartate aminotransferase. Aspartate aminotransferase from Escherichia coli bound with cofactor pyridoxal 5-phosphate (PDB 1AAM)

Genetic data
Gene code: [1] ID#: GI:41011
Protein Structure/Function
Structure: [2]1AAM
Related information
Recent publications: [3]

Aspartate aminotransferase of Escherichia coli: nucleotide sequence of the aspC gene.,
[4] The complete amino acid sequence of aspartate aminotransferase from Escherichia coli: sequence comparison with pig isoenzymes.,
[5]Site-directed mutagenesis of Escherichia coli aspartate aminotransferase: role of Tyr70 in the catalytic processes.

Aspartate Transaminase (AST) also called Serum Glutamic Oxaloacetic Transaminase (SGOT) or aspartate aminotransferase (ASAT/AAT) (EC 2.6.1.1) is similar to alanine transaminase (ALT) in that it is another enzyme associated with liver parenchymal cells. It is raised in acute liver damage. It is also present in red blood cells and cardiac muscle.

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