Apyrase

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Apyrase is a calcium-activated plasma membrane-bound enzyme (magnesium can also activate it) (EC 3.6.1.5) that catalyses the hydrolysis of ATP to yield AMP and pyrophosphate. It can also act on ADP and other nucleoside triphosphates and diphosphates. It is the enzyme released by female mosquitoes to prevent blood clots when they suck blood. (Products usually extracted from plants.) The activity of apyrase at pH 7.5 in a Tris Buffer is approximately 80% of the activity at pH 6.5.