Antianalgesia

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Antianalgesia is the ability of some endogenous chemicals (notably cholecystokinin and neuropeptide Y) to counter the effects of exogenous analgesics (such as morphine) or endogenous pain inhibiting neurotransmitters/modulators, such as the endogenous opioids.[1] A learned form can be established using methods similar to the learning principle of conditioned inhibition, and has been demonstrated in rats.

[edit] References

  1. ^ Wiertelak, EP; Maier, SF and Watkins, LR (8 May 1992). "Cholecystokinin antianalgesia: safety cues abolish morphine analgesia". Science 256 (5058): 830 - 833. DOI:10.1126/science.1589765. Retrieved on 2007-02-12. 


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