Angiotensin-converting enzyme 2
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Angiotensin I converting enzyme 2
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Identifiers | |
Symbol | ACE2 ACEH |
HUGO | 13557 |
Entrez | 59272 |
OMIM | 300335 |
RefSeq | NM_021804 |
UniProt | Q9BYF1 |
Other data | |
Locus | Chr. X p22 |
Angiotensin I converting enzyme 2 (ACE2) is an exopeptidase that catalyses the conversion of angiotensin I to the nonapeptide angiotensin[1-9] [1]. ACE 2 has direct effects on cardiac function[2], and is expressed predominantly in vascular endothelial cells of the heart and the kidneys [1].
[edit] See also
[edit] References
- a b Donoghue M, Hsieh F, Baronas E, Godbout K, Gosselin M, Stagliano N, Donovan M, Woolf B, Robison K, Jeyaseelan R, Breitbart RE, Acton S. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9. Circ Res 2000;87:E1-9. PubMed Free text
- a Boehm M, Nabel EG. Angiotensin-converting enzyme 2--a new cardiac regulator. N Engl J Med 2002;347:1795-7. PubMed