Alpha-Ethyltryptamine

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α-Ethyltryptamine (α-ET)
Chemical name 1-(1H-indol-3-yl)butan-2-amine
Chemical formula C12H16N2
Molecular mass 188.27 g/mol
Melting point 104 - 105 °C (base)
222 - 223 °C (hydrochloride)
CAS numbers 2235-90-7, 6152-12-1,
10215-73-3, 29854-47-5
SMILES NC(CC)CC1=CNC2=C1C=CC=C2
Chemical structure of alpha-ethyltryptamine

alpha-Ethyltryptamine, also known as α-ethyltryptamine, α-ET, or AET, is a psychoactive drug belonging to the tryptamine family. It was explored as an anti-depressant by Upjohn Chemical Company under the name Monase, but was withdrawn from commercial use after a year due to the unacceptable occurence of agranulocytosis. It was moved into US Schedule I list of illegal substances in 1993. It is structurally related to α-methyltryptamine but its pharmacological effects are very different. α-ET is not a hallucinogenic drug, its effects resemble more that of the empathogen-entactogens like MDMA (Ecstasy). Alexander Shulgin, in TiHKAL, mentions that this compound has been used to alleviate unpleasant symptoms of opiate withdrawal.

[edit] Dosage

75-150 mg is commonly consumed orally for entactogenic effects. α-ET has a stereocenter and S-(+)-α-ET is the more active stereoisomer.

[edit] See also

[edit] External links


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